If Omicron turns out to have substantial immune evasiveness, the pills will add a significant layer of defense. We should get these small molecules into mass production, especially Paxlovid, with its takedown of upstream Mpro, and much higher efficacy than Molnupiravir (to date) https://t.co/uxFKD27brV https://t.co/XLk7WtarPf
— Eric Topol (@EricTopol)
Nov 28, 2021
from http://twitter.com/EricTopol
How any advertiser can stick with this network’s insanely dangerous antivaxx rhetoric, especially in light of the fact that Fox has their own COVID protocols, is absolutely stunning. https://t.co/H34fLRXy2F
— Sleeping Giants (@slpng_giants)
Nov 28, 2021
from http://twitter.com/slpng_giants
As we await more data on #Omicron
If you are an vaccinated adult (6 months out)
This is a good time to go get a booster
It’ll dramatically reduce your risk of infection from Delta (still the biggest threat by far)
And will likely increase your protection against #Omicron
— Ashish K. Jha, MD, MPH (@ashishkjha)
Nov 28, 2021
from http://twitter.com/ashishkjha
Lotta folks in the take industry writing stuff like “Here’s everything you need to know about the omicron variant” when the actual experts are saying stuff like “we don’t know anything about the omicron variant.”
— Christopher Ingraham (@_cingraham)
Nov 28, 2021
from http://twitter.com/_cingraham
@toddkaminsky Friends, work with Kaminsky & other govt officials to have the Proud Boys listed as a domestic terrorist organization, as the people & govt of Canada have already done.
https://t.co/KOISvCzo1i
— Rochelimit2772 (@rochelimit2772)
Nov 28, 2021
from http://twitter.com/rochelimit2772
We’ll know much more about Omicron soon……
Excellent summary of where we stand, including the lab tests underway, by @kakape @ScienceMagazine
https://t.co/7ypVVGvYPG https://t.co/N4rTIty9z8— Eric Topol (@EricTopol)
Nov 27, 2021
from http://twitter.com/EricTopol
Ten percent prevalence on those flights almost defies imagination. I expected far lower. But it might not be entirely bad news. If we have extraordinary prevalence without a huge hospitalization/mortality spike in South Africa, omicron may be less virulent than previous variants. https://t.co/0iiT0oVmko
— Carl T. Bergstrom (@CT_Bergstrom)
Nov 27, 2021
from http://twitter.com/CT_Bergstrom
Thank you, Trump voters. https://t.co/XUL6Hux2wr
— David Corn (@DavidCornDC)
Nov 27, 2021
from http://twitter.com/DavidCornDC
It’s worth pointing out that any long-term strategy that puts vaccines first puts us behind new variant’s OODA loop. We’re reacting to damage done by an entrenched threat. Masks, filters, UVGI, ventilation+CO2 tests work against *all* varients and should lead mitigation efforts. https://t.co/nZhx7UJ5Vs
— Naomi Wu 机械妖姬 (@RealSexyCyborg)
Nov 27, 2021
from http://twitter.com/RealSexyCyborg
Some statements today said the new variant “displaced” or “out-competed” delta in South Africa. But delta had largely run its course. Prevalence was very low.
More likely the new variant emerged from some initial clusters and super-spread events — and then gained a foothold. https://t.co/2M0TAE10gz
— Scott Gottlieb, MD (@ScottGottliebMD)
Nov 26, 2021
from http://twitter.com/ScottGottliebMD
#1: Consider vax status + risk level of your guests and clearly communicate expectations and rules. There is still time!
Vaxxed and boosted is best, but not possible for everyone. Remember that immunocompromised + elderly are at greater risk + require more layers of protection.
— Dr. Anne Rimoin (@arimoin)
Nov 25, 2021
from http://twitter.com/arimoin
“…The CDC recommended last week that all adults be made eligible for booster shots but only urged shots for people older than 50.
That was a big mistake. It should have urged all adults to get them.” @EricTopol @mtosterholm @PostOpinions
100% agree.
https://t.co/bvkVNtekgZ
— Leana Wen, M.D. (@DrLeanaWen)
Nov 24, 2021
from http://twitter.com/DrLeanaWen
if you’re at Thanksgiving and someone says their decision to not get vaccinated doesn’t affect anyone else, cut your slice of pie like this to demonstrate how that is very untrue https://t.co/PFq95dJ2vA
— Josh Trebach, MD (@jtrebach)
Nov 23, 2021
from http://twitter.com/jtrebach
Covid vaccination rates vs death rates in Europe. There appears to be an inflection point around 75%. (The US is currently at 71%.) https://t.co/Z8kFkDYIug
— kottke.org (@kottke)
Nov 23, 2021
from http://twitter.com/kottke
Just published @ScienceMagazine
The remarkably tight correlation of neutralizing antibody levels with protection from an mRNA vaccine (@moderna_tx)
https://t.co/eg3xITH3Z2
Titer/Vacccine efficacy
10/78%
100/91%
1000/96% https://t.co/ghjA8WRP6I— Eric Topol (@EricTopol)
Nov 23, 2021
from http://twitter.com/EricTopol
More proof that vaccine mandates work! This should encourage even more employers to protect their workers and their communities by requiring vaccinations.
https://t.co/4lsBtKAcHO
— Zeke Emanuel (@ZekeEmanuel)
Nov 22, 2021
from http://twitter.com/ZekeEmanuel
Updated data on COVID Data Tracker show ppl not vaccinated for #COVID19 are:
-6x more likely to test positive,
-14x more likely to die from #COVID19, &
-Have 9x higher rate of COVID-19 associated hospitalization compared to those vaccinated. Get vaccinated https://t.co/bfOV5VRcgY https://t.co/YoXG8G4PG4— Rochelle Walensky, MD, MPH (@CDCDirector)
Nov 22, 2021
from http://twitter.com/CDCDirector
Covid has made the public more familiar w/ benefit-risk calculations–for vax, it’s hugely positive.
In Aduhelm, we have a med w/ unproven clinical benefit & now some scary safety signals. Oh, and its projected cost adds ~$120/yr to everyone’s Medicare premium. FDA blew this one. https://t.co/jZj3PHx1NG— Bob Wachter (@Bob_Wachter)
Nov 22, 2021
from http://twitter.com/Bob_Wachter
Booster eligibility can still be confusing
So here’s my guide to help you decide whether you should get a booster 6 months after your 2nd shot:
Are you an adult?
If yes, get a booster
— Ashish K. Jha, MD, MPH (@ashishkjha)
Nov 22, 2021
from http://twitter.com/ashishkjha
A classic tactic COVID deniers use?
Compare COVID risk for young people to COVID risks for older people
That’s not how this works
In medicine, we compare a person’s risk (from COVID lets say) to other risks that person faces
And in that light, COVID is bad for young people https://t.co/ohZxF8OANi
— Ashish K. Jha, MD, MPH (@ashishkjha)
Nov 22, 2021
from http://twitter.com/ashishkjha
Today @CDCgov updated their website for cases and deaths by vaccine status, vaccine, and age; national data for 36% of the US population
https://t.co/HGyjNwCm0v
Unvaccinated: 14-fold increased risk of death, 5.8-fold risk of infection, compared with fully vaccinated https://t.co/DSn8LEzrQJ— Eric Topol (@EricTopol)
Nov 22, 2021
from http://twitter.com/EricTopol
Still hearing people cite COVID breakthrough infections as proof vaccines don’t really work.
This graphic illustrates nicely why that is argument wrong.
I.e., the vaccine works!
Here’s a quick thread on why … 🧵💉 (1) https://t.co/y1JsavjRHA
— Jonathan Cohn (@CitizenCohn)
Nov 22, 2021
from http://twitter.com/CitizenCohn
Preprint from @NorthwesternU team:
💉 3rd booster dose has 23x ↑ in protective neutralizing antibodies compared to after 2nd shot
🦠 2 shots + getting covid is no better protection than two vaccines and no covid
👉🏻 https://t.co/rndcnAE18f https://t.co/W3WxAlP8Kb
— Christopher A. Longhurst (@calonghurst)
Nov 28, 2021
from http://twitter.com/calonghurst
Many thanks @holmescnn for hosting me on @cnni to discuss #Omicronvariant:
-what we need to know to understand the threat it poses
-the need for ⬆️ genomic surveillance + testing
-the minimal impact of travel bans
-vaccine equity, access + hesitancy.We covered a lot of ground! https://t.co/UH66Uzrd0e
— Dr. Anne Rimoin (@arimoin)
Nov 28, 2021
from http://twitter.com/arimoin
1) My gut feeling from hearing of Omicron cases in Botswana, ex-Malawi, ex-Egypt (2 now it seems) and in South Africa is, that the variant was flying under the radar in undersequenced countries for some time until Botswana and South Africa detected it and sounded the alarm.
— Florian Krammer (@florian_krammer)
Nov 27, 2021
from http://twitter.com/florian_krammer
We gotta free the vaccines.
— Dave Pell (@davepell)
Nov 27, 2021
from http://twitter.com/davepell
Some Kellogg’s workers are asking the public to stop buying Kellogg’s products as workers have been on strike for two months and the company is working to replace them rather than negotiate a fair contract.
This is a beautiful post from a workers’ wife on the strike https://t.co/sJE5759qvl
— Michael Sainato (@msainat1)
Nov 27, 2021
from http://twitter.com/msainat1
While it may seem like the decay in vax efficacy over 6 months portends a future of every-6-month boosting, the immune system doesn’t work like that. There’s every reason to believe shot #3 will last one or more years. Alas, there’s no way to know other than to see what happens.
— Bob Wachter (@Bob_Wachter)
Nov 21, 2021
from http://twitter.com/Bob_Wachter
As we continue to head-scratch about getting unvaccinated people vaxxed, I’m struck by the crickets coming out of health & life insurance industries. Seems like vax is a volitional act that either increases (raise premiums) or lowers (cut them) a person’s risk of illness & death.
— Bob Wachter (@Bob_Wachter)
Nov 20, 2021
from http://twitter.com/Bob_Wachter
As the US begins its 5th wave with 59% vaccinated, Canada, with 76% vaccinated, shows no sign of increased spread
Death rate 🇺🇸 5.3-fold 🇨🇦
Hospitalizations 🇺🇸3-fold 🇨🇦
New cases 🇺🇸 >4-fold🇨🇦
@OurWorldInData https://t.co/IT6W4sIpmw— Eric Topol (@EricTopol)
Nov 20, 2021
from http://twitter.com/EricTopol